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Brefeldin A

CAS 号: 20350-15-6 (中文同义词:布雷非德菌素 A)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00054

分子式:C16H24O4

分子量:280.36

纯度:≥99%

长期储存条件:Store in a tight container at -20℃.

描述:Protein trafficking inhibitor;Antitumor, Antiviral

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规格 价格 (EXW) 是否有货 数量 加入购物车
50mg ¥1150.00 有货 - 1 +
100mg ¥1880.00 有货 - 1 +
500mg ¥7560.00 有货 - 1 +
1g ¥10450.00 有货 - 1 +
生物活性
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.Brefeldin A (BFA) is a fungal metabolite. It exhibits a wide range of antibiotic activity.
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参考文献

[1] Kaczmarek B, Verbavatz JM, Jackson CL. GBF1 and Arf1 function in vesicular trafficking, lipid homoeostasis and organelle dynamics. Biol Cell. 2017 Dec;109(12):391-399. doi: 10.1111/boc.201700042. Epub 2017 Nov 6. Review. PubMed PMID: 28985001.

[2] Valente C, Luini A, Corda D. Components of the CtBP1/BARS-dependent fission machinery. Histochem Cell Biol. 2013 Oct;140(4):407-21. doi: 10.1007/s00418-013-1138-1. Epub 2013 Sep 1. Review. PubMed PMID: 23996193.

[3] Foulquier F. COG defects, birth and rise! Biochim Biophys Acta. 2009 Sep;1792(9):896-902. doi: 10.1016/j.bbadis.2008.10.020. Epub 2008 Nov 6. Review. PubMed PMID: 19028570.

[4] Arduino D, Silva D, Cardoso SM, Chaves S, Oliveira CR, Santos MA. New hydroxypyridinone iron-chelators as potential anti-neurodegenerative drugs. Front Biosci. 2008 May 1;13:6763-74. Review. PubMed PMID: 18508693.

[5] Nozawa N, et al. Subcellular localization of herpes simplex virus type 1 UL51 protein and role of palmitoylation in Golgi apparatus targeting. J Virol. 2003 Mar;77(5):3204-16.

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