It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L.