CAS 号: 57710-57-3 (中文同义词:庚萜酸)
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It is produced by the strain of Gliocladium virens, Chaetomium globosum, Trichoderma viride. It is a sesquiterpenoid antibiotic. It has antibacterial activity against anaerobes, especially has strong effect on fragile bacilli (MIC is 0.4 μg/mL). It has anti-plasmodium (IC80 is 0.01 μg/mL) and antitumor activity. It is also an inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) that acts by binding to the cysteine-149 residue.
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