CAS 号： 39389-47-4 （中文同义词：偏端霉素 A）
所有产品仅用于科学研究，不得用于人体或动物实验。
目录号：HD00023
分子式：C22H27N9O4
分子量：481.51
纯度：≥90%
长期储存条件：Store in a tight container at -20℃.
描述：Anticancer antibiotic，antiviral and antiprotozoal activity.
Distamycin is an antibiotic that binds the minor groove of duplex DNA at AT‐rich regions and induces a specific activation of transcriptional initiation by binding to non-alternating AT sequences in the spacer DNA.
[1] Cocco M J, Hanakahi L A, Huber M D, et al. Specific interactions of distamycin with G‐quadruplex DNA[J]. Nucleic acids research, 2003, 31(11): 2944-2951.
[2] Khalaf A I, Waigh R D, Drummond A J, et al. Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity[J]. Journal of medicinal chemistry, 2004, 47(8): 2133-2156.
[3] Dorn A, Affolter M, Müller M, et al. Distamycin‐induced inhibition of homeodomain‐DNA complexes[J]. The EMBO journal, 1992, 11(1): 279-286.
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