Fidaxomicin is sourced from Dactylosporum aurantiacum. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.

[1] Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. Parenti F. et al. J. Antibiot. 1975, 28, 247.

[2] Clostomicins, new antibiotics produced by Micromonospora echinospora subsp. armeniaca subsp. nov. I. Production. Omura S. et al. J. Antibiot. 1986, 39, 1407.

[3] Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I. Taxonomy, fermentation and antibacterial activity. Theriault R.J. et al. J. Antibiot. 1987, 40, 567.