CAS 号： 119509-24-9 （中文同义词：抗癣青霉素 A5）
所有产品仅用于科学研究，不得用于人体或动物实验。
目录号：HD00040
分子式：C15H21Cl2NO5
分子量：366.24
纯度：≥95%
长期储存条件：Store in a tight container at -20℃.
描述：Antifungal antibiotic isolated from Penicillium sp.
Originally isolated from Penicillium sp. strain. An antibiotic and antifungal agent. Highly selective, potent ubiquinone-binding site mitochondrial complex II inhibitor (IC50 values are 12 and 3.7 nM for nematode and mammalian mitochondria respectively). Stimulates mitochondrial KATP channels. Shows anti-ischemic and cardioprotective effects in vivo.
[2] Hiroko Miyadera, et al. Atpenins, potent and specific inhibitors of mitochondrial complex II (succinateubiquinone oxidoreductase). PNAS, 2003, 100(2): 473-477.
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