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Ascomycin

CAS 号: 104987-12-4 (中文同义词:子囊霉素)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00032

分子式:C43H69NO12

分子量:792.01

纯度:≥95%

长期储存条件:Store in a tight container at -20℃.

描述:Immunity inhibitor

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规格 价格 (EXW) 是否有货 数量 加入购物车
50mg ¥778.00 有货 - 1 +
100mg ¥1380.00 有货 - 1 +
250mg ¥2760.00 有货 - 1 +
生物活性

Ascomycin, a well-known immunosuppressant and antifungal, is used for the treatment of autoimmune diseases and skin diseases, and to prevent organ rejection after transplant. Apart from active pharmaceutical ingredient, Ascomycin is useful as a key starting material for the synthesis of Pimecrolimus (Kumar et al., 2007). Ascomycin is produced industrially by microbial fermentation through Streptomyces hygroscopicus subsp. ascomyceticus. 

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参考文献

[1] Kumar, P., Sharma, S.K., Malviya, H.K., Balasubramaniam, R.C., Dalal, A., 2007. An Improved Fermentation Process for Preparing Ascomycin. WO 2007/029082.

[2] Tadashi et al. (1966) reported an antifungal agent identified as ascomycin which is prepared by the process which comprises cultivating a strain of Streptomyces hygroscopicus var.ascomyceticus under submerged aerobic condition.

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