CAS 号: 11015-37-5 (中文同义词:黄霉素)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00111
分子式:C69H107N4O35P
分子量:1583.57
纯度:≥95%
长期储存条件:Store in a tight container at -20°C.
描述:Cell Wall Synthesis Inhibitor
Moenomycin is a natural product glycolipid that inhibits the growth of a broad spectrum of Gram-positive bacteria. Moenomycin inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs), which are key enzymes in bacterial cell wall synthesis.
[1] Eugene R. Baizman, Arthur A. Branstrom, Clifford B. Longley, Nigel Allanson, a, Michael J. Sofia,b, David Gange, Robert C. Goldman, Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase, Microbiology (2000), 146, 3129–3140
[2] Bohdan Ostash, Suzanne Walker, Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity, Nat Prod Rep. 2010 Nov;27(11):1594-617. doi: 10.1039/c001461n. Epub 2010 Aug 23.
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