CAS 号： 53123-88-9 （中文同义词：雷帕霉素，西罗莫司）
所有产品仅用于科学研究，不得用于人体或动物实验。
目录号：HD00123
分子式：C51H79NO13
分子量：914.17
纯度：≥95%
长期储存条件：Store in a tight container between 2-8℃, protect from light.
描述：Potent and specific mTOR inhibitor
Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor . Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC. Rapamycin is an autophagy activator, an immunosuppressant.
[1] Edwards SR, et al. The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain. J Biol Chem, 2007, 282(18), 13395-13401.
[2] Rangaraju S, et al. Rapamycin activates autophagy and improves myelination in explant cultures from neuropathicmice. J Neurosci. 2010 Aug 25;30(34):11388-97.
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