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Cynaroside

CAS 号: 5373-11-5 (中文同义词:木犀草苷)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00153

分子式:C21H20O11

分子量:448.38

纯度:≥95%

长期储存条件:Store in a tight container at -20°C.

描述:Flavonoid compound, an influenza-dependent RNA polymerase inhibitor

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生物活性
Cynaroside (Luteolin 7-glucoside) is a flavonoid that has been found in many Chinese herbs with diverse biological activities and also a potent influenza RNA-dependent RNA polymerase inhibitor.
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参考文献

[1] Liu, Z., Yang, L., Huang, J., et al. Luteoloside attenuates anoxia/reoxygenation-induced cardiomyocytes injury via mitochondrial pathway mediated by 14-3-3η protein. Phytother. Res. 32(6), 1126-1134 (2018).

[2] Cao, Z., Ding, Y., Ke, Z., et al. Luteoloside acts as 3C protease inhibitor of enterovirus 71 in vitro. PloS One 11(2), e0148693 (2016).

[3] Václav Zima, et al. Unraveling the Anti-Influenza Effect of Flavonoids: Experimental Validation of Luteolin and its Congeners as Potent Influenza Endonuclease Inhibitors. Eur J Med Chem. 22 August 2020, 112754.

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