CAS 号: 1149-99-1 (中文同义词:隐陡头菌素S)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00064
分子式:C15H20O4
分子量:264.32
纯度:≥95%
长期储存条件:Store in a tight container at -20℃.
描述:DNA Alkylator
Illudin S is a cytotoxic Illudin, a genetically toxic natural sesquiterpene with strong anti-tumor and anti-viral activities. Illudin S blocks the G1-S phase interface of the human leukemia cell cycle.
[1] Glatt H, Pietsch KE, Sturla SJ, Meinl W. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol. 2014 Jan;88(1):161-9.
[2] Tanaka K, Inoue T, Kadota S, Kikuchi T. Metabolism by rat liver cytosol of illudin S, a toxic substance of Lampteromyces japonicus. II. Characterization of illudin S-metabolizing enzyme. Xenobiotica. 1992 Jan;22(1):33-9.
[3] Pietsch KE, van Midwoud PM, Villalta PW, Sturla SJ. Quantification of acylfulvene- and illudin S-DNA adducts in cells with variable bioactivation capacities. Chem Res Toxicol. 2013 Jan 18;26(1):146-55.
您是第 1979690 位访问者
电话:0086-571-89903882
邮箱:hdcsales@huidacollection.cn
Copyright © 2021 浙江珲达生物科技有限公司 浙ICP备20008217-2号 Designed by Wanhu 公安备案号 33010502006723