CAS 号: 62182-86-9 (中文同义词:二氢洋红霉素)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00026
分子式:C26H29NO10
分子量:515.52
纯度:≥98%
长期储存条件:Store in a tight container at -20℃.
描述:Anthracycline antibiotic
Dihydrocarminomycin is an anthracycline antibiotic that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
[1] Shepelevtseva N G, Belova I P, Vertogradova T P, et al. Comparative study of the cardiotoxicity of the anthracycline antibiotics, rubomycin, carminomycin and dihydrocarminomycin, in experiments on white mice. Antibiotiki. 1978 Jan;23(1):78-87.
[2] Povarov L S,Shorin V A,Bazhanov V S,Shepelevtseva N G.Preparation of dihydrocarminomycin and a comparison of its antitumor activity with the activity of carminomycin.[J]. Antibiotiki,1976,21(11):1008-11.
[3] Dudnik IuV, Ostanina LN. Interaction with DNA of semisynthetic carminomycin and rubomycin derivatives. Antibiotiki. 1983 Jan;28(1):31-6.
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