Epothilone C belong to the epothilone family of compounds which is a group of polyketide natural products produced by the myxobacterium Sorangium cellulosum. Mechanism wise similar to taxanes, epothilones fight cancer cells by interfering with tubulin.

[1] Cheng K, Bradley T, Budman D R, et al. Novel microtubule-targeting agents - the epothilones[J]. Biologics: Targets & Therapy, 2008, 2(4): 789-811.

[2] Boddy C N, Schneider T L, Hotta K, et al. Epothilone C Macrolactonization and Hydrolysis Are Catalyzed by the Isolated Thioesterase Domain of Epothilone Polyketide Synthase[J]. Journal of the American Chemical Society, 2003, 125(12): 3428-3429.