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Doramectin

CAS 号: 117704-25-3 (中文同义词:多拉菌素)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00142

分子式:C50H74O14

分子量:899.11

纯度:≥95%

长期储存条件:Store in a tight container between 2-8℃.

描述:Major inhibitory neurotransmitter

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Doramectin is an antiparasitic drug for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.

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参考文献

[1] Lumaret JP, Errouissi F, Floate K, Römbke J, Wardhaugh K. A review on the toxicity and non-target effects of macrocyclic lactones in terrestrial and aquatic environments. Curr Pharm Biotechnol. 2012 May;13(6):1004-60. Review. PubMed PMID: 22039795; PubMed Central PMCID: PMC3409360.

[2] Davey RB, Pound JM, Klavons JA, Lohmeyer KH, Freeman JM, Olafson PU. Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion. Exp Appl Acarol. 2012 Apr;56(4):365-74. doi: 10.1007/s10493-012-9525-1.

[3] Wang XJ, Zhang J, Wang JD, Huang SX, Chen YH, Liu CX, Xiang WS. Four new doramectin congeners with acaricidal and insecticidal activity from Streptomyces avermitilis NEAU1069. Chem Biodivers. 2011 Nov;8(11):2117-25. doi: 10.1002/cbdv.201000295.

[4] Gordana Panic, et al. Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni. PLoS Negl Trop Dis. 2015 Jul 31;9(7):e0003962.

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