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2'-Fluoro-2'-Deoxyguanosine

CAS 号: 78842-13-4 (中文同义词:2'-氟-2'-脱氧鸟苷)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00082

分子式:C10H12FN5O4

分子量:285.23

纯度:≥95%

长期储存条件:Store in a tight container between 2-8℃.

描述:Building blocks of nucleic acid

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2'-Fluoro-2'-Deoxyguanosine, a nucleoside analog, is a potent inhibitor of influenza virus A and B strains. 2'-Fluoro-2'-Deoxyguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation.

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参考文献

[1] Tisdale M, et, al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8. 

[2] Jakeman KJ, et, al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7.

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