4'-Methylchrysoeriol is a potent inhibitor of P450 enzymes, particularly for P450 1B1, with an IC50 of 19 nM for human P450 1B1-dependent EROD.

[1] Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22(7):1325-33.