CAS 号: 52705-93-8 (中文同义词:人参皂苷 Rd)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00194
分子式:C48H82O18
分子量:947.15
纯度:≥95%
长期储存条件:Store in a tight container at -20℃.
描述:26S proteasome inhibitor and TRPm7 antagonist
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Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Ginsenoside Rd may have properties that inhibit or prevent the growth of tumors.
[1] Chen, C.F., Chiou, W.F., and Zhang, J.T. Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium. Acta.Pharmacol.Sin. 29(9), 1103-1108 (2008).
[2] Wang, Y., Li, X., Wang, X., et al. Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathway. PLoS One 8(8), e70956 (2013).
[3] Liu, X., Wang, L., Wen, A., et al. Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur.J.Neurol. 19(6), 855-863 (2012).
[4] Song, S.B., Tung, N.H., Quang, T.H., et al. Inhibition of TNF-α-mediated NF-κB transcriptional activity in HepG2 cells by dammarane-type saponins from Panax ginseng leaves. J.Ginseng Res. 36(2), 146-152 (2012).
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