CAS 号: 80418-24-2 (中文同义词:三七皂苷 R1)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00218
分子式:C47H80O18
分子量:933.13
纯度:≥95%
长期储存条件:Store in a tight container at -20℃.
描述:Saponin, isolated from P. notoginseng
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Notoginsenoside R1 (NGR1) is a novel saponin isolated from P. notoginseng. Notoginsenoside R1 possesses antioxidant, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection effects against I/R injuries. Notoginsenoside R1 can reduce reactive oxygen species and confer some neuroprotective effects.
[1] Yingli Yu, Guibo Sun, Yun Luo, Min Wang, Rongchang Chen, Jingyi Zhang, Qidi Ai, Na Xing, Xiaobo Sun, Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways. Sci Rep. 2016 Feb 18;6:21730. doi: 10.1038/srep21730.
[2] Bo Ma, Xiangbao Meng, Jing Wang, Jing Sun, Xiaoyu Ren, Meng Qin, Jie Sun, Guibo Sun, Xiaobo Sun. Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. Int Immunopharmacol. 2014 Sep;22(1):151-9. doi: 10.1016/j.intimp.2014.06.018. Epub 2014 Jun 24.
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