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PF1022A

CAS 号: 133413-70-4

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00226

分子式:C52H76N4O12

分子量:949.18

纯度:≥95%

长期储存条件:Store in a tight container at -20℃.

描述:Anthelmintic depsipeptide isolated from Mycelia Sterilia

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PF1022A is a novel anthelmintic cyclodepsipeptide which was isolated from cultured mycelia of Mycelia Sterilia. It showed strong anthelmintic activities against Ascaridia galli in chickens. PF1022A acts as an ionophore.

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参考文献

[1] T Sasaki, M Takagi, T Yaguchi, S Miyadoh, T Okada, M Koyama. A new anthelmintic cyclodepsipeptide, PF1022A. J Antibiot (Tokyo). 1992 May;45(5):692-7. doi: 10.7164/antibiotics.45.692.

[2] R Dornetshuber, M R Kamyar, P Rawnduzi, I Baburin, K Kouri, E Pilz, T Hornbogen, R Zocher, W Berger, R Lemmens-Gruber. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44. doi: 10.1016/j.bcp.2009.01.005. Epub 2009 Jan 21.

[3] Uzoma Nwosu, Mireille Vargas, Achim Harder, Jennifer Keiser. Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology. 2011 Aug;138(9):1193-201. doi: 10.1017/S003118201100076X. Epub 2011 Jul 15.

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