CAS 号： 133413-70-4
所有产品仅用于科学研究，不得用于人体或动物实验。
目录号：HD00226
分子式：C52H76N4O12
分子量：949.18
纯度：≥95%
长期储存条件：Store in a tight container at -20℃.
描述：Anthelmintic depsipeptide isolated from Mycelia Sterilia
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PF1022A is a novel anthelmintic cyclodepsipeptide which was isolated from cultured mycelia of Mycelia Sterilia. It showed strong anthelmintic activities against Ascaridia galli in chickens. PF1022A acts as an ionophore.
[1] T Sasaki, M Takagi, T Yaguchi, S Miyadoh, T Okada, M Koyama. A new anthelmintic cyclodepsipeptide, PF1022A. J Antibiot (Tokyo). 1992 May;45(5):692-7. doi: 10.7164/antibiotics.45.692.
[2] R Dornetshuber, M R Kamyar, P Rawnduzi, I Baburin, K Kouri, E Pilz, T Hornbogen, R Zocher, W Berger, R Lemmens-Gruber. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44. doi: 10.1016/j.bcp.2009.01.005. Epub 2009 Jan 21.
[3] Uzoma Nwosu, Mireille Vargas, Achim Harder, Jennifer Keiser. Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology. 2011 Aug;138(9):1193-201. doi: 10.1017/S003118201100076X. Epub 2011 Jul 15.
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