CAS 号: 77327-05-0 (中文同义词:膜海鞘素B)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00004
分子式:C57H89N7O15
分子量:1112.35
纯度:≥95%
长期储存条件:Store in a tight container at -20°C.
描述:A depsipeptide, antiviral and antineoplastic
Didemnin B is a cyclic depsipeptide with antiviral and antitumor activity.
[1] Biologically active depsipeptides extracted from a Caribbean tunicate (sea squirt) family Didemnidae, genus Trididemnum. First marine natural product to enter clinical trials as antineoplastic. The three components, didemnins A, B and C are weakly basic compds with antiviral, antitumor activity. Didemnin A is the most abundant, whereas didemnin B is generally the most active.
[2] Isoln and bioactivity: K. L. Rinehart, Jr. et al., Science 212, 933 (1981).
[3] Extraction and purification: K. L. Rinehart, Jr., EP 48149; idem, US 4493796 (1982, 1985 both to Univ. Illinois).
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