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Schisandrin B

CAS 号: 61281-37-6 (中文同义词:五味子乙素)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00409

分子式:C23H28O6

分子量:400.46

纯度:≥95%

长期储存条件:Store in a tight container at -20℃.

描述:The active substance extracted from Schisandra chinensis

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Schisandrin B, a dibenzocyclooctadiene derivative isolated from Schisandra chinensis and uses in traditional Chinese medicine for the treatment of hepatitis and myocardial disorders. The anti-inflammatory effects of Schisandrin B are mediated via modulation of Nrf2 and NF-κB in lymphocytes.

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[1] Checker R, et al. Schisandrin B exhibits anti-inflammatory activity through modulation of the redox-sensitive transcription factors Nrf2 and NF-κB. Free Radic Biol Med. 2012 Oct 1;53(7):1421-30.

[2] Lam PY, et al. Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases. Oxid Med Cell Longev. 2012;2012:250825.

[3] Zeng KW, et al. Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide-induced microglia. Eur J Pharmacol. 2012 Oct 5;692(1-3):29-37.

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