CAS 号: 56377-79-8 (中文同义词:那西肽)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00222
分子式:C51H43N13O12S6
分子量:1222.36
纯度:≥95%
长期储存条件:Store in a tight container at -20℃.
描述:Thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein
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Nosiheptide exhibited extremely potent activity against all contemporary MRSA strains tested including multiple drug-resistant clinical isolates, with MIC values 0.25 mg l(-1). Nosiheptide was also highly active against Enterococcus spp. Nosiheptide has been widely used as a feed additive for animal growth.
[1] Haste NM, et al. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2012 Dec;65(12):593-8.
[2] Yu Y, et al. Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. ACS Chem Biol. 2009 Oct 16;4(10):855-64.
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