7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid compound with anti-inflammatory, antipyretic, antitussive, anti-diabetic, anti- Cancer and anti-melanogenesis properties. In a concentration-dependent manner, it significantly reduces the production of pro-inflammatory cytokines, such as TNF-α, IL-6 and IL-1β.

[1] Sudha, A, et al. Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation. Medicinal Chemistry Research, 2016,25(9), 1754–1767.