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当前位置:首页 > 产品中心 > 免疫抑制剂 > Everolimus
Everolimus

CAS 号: 159351-69-6 (中文同义词:依维莫司)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00423

分子式:C53H83NO14

分子量:958.22

纯度:≥95%

长期储存条件:Store in a tight container at -20℃.

描述:Derivatives of rapamycin

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Everolimus is an inhibitor of the mammalian target of rapamycin (mTOR) and has been shown to have antineoplastic activity in addition to its use as an immunosuppressive agent for the prevention of organ transplant rejection. Besides its immunosuppressive activity for the prevention of organ transplant rejection, everolimus exhibits antineoplastic activity and is currently used to treat renal cell cancer and other tumors.

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参考文献

[1] Laura Eibenschutz, Delia Colombo, Caterina Catricalà. Everolimus for compassionate use in multiple Basal cell carcinomas. Case Rep Dermatol Med. 2013;2013:604301. doi: 10.1155/2013/604301.

[2] G Anandappa, AE Hollingdale, and TG Eisen. Everolimus – a new approach in the treatment of renal cell carcinoma. Cancer Management and Research 2010:2 61-70

[3] Raffaele Pezzani, Beatrice Rubin, Marco Redaelli, Claudia Radu, Susi Barollo, Maria Verena Cicala, Monica Salva, Caterina Mian, Carla Mucignat-Caretta, Paolo Simioni, Maurizio Iacobone and Franco Mantero. The antiproliferative effects of ouabain and everolimus on adrenocortical tumor cells. Endocrine journal, 2013

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