CAS 号： 1393-48-2 （中文同义词：硫链丝菌素）
所有产品仅用于科学研究，不得用于人体或动物实验。
目录号：HD00371
分子式：C72H85N19O18S5
分子量：1664.89
纯度：≥95%
长期储存条件：Store in a tight container at -80℃, away from moisture.
描述：A thiazole antibiotic which selectively inhibits FOXM1.
| 规格 | 价格 (EXW) | 是否有货 | 数量 | 加入购物车 |
|---|
Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation.
[1] Ajaybabu V Pobbati, et al. A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy. Theranostics. 2020 Feb 18;10(8):3622-3635.
[2] Xuan Zhang, et al. Targeting of mutant p53-induced FoxM1 with Thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells. Oncotarget. 2014 Nov 30;5(22):11365-80.
[3] Aniruddha Sengupta, et al. The dual inhibitory effect of Thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing's sarcoma. Int J Oncol. 2013 Sep;43(3):803-12.
您是第 1979506 位访问者
电话：0086-571-89903882
邮箱：hdcsales@huidacollection.cn
Copyright © 2021 浙江珲达生物科技有限公司
浙ICP备20008217-2号
Designed by Wanhu 
公安备案号 33010502006723