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5-Ethynyl-2'-Deoxyuridine

CAS 号: 61135-33-9 (中文同义词:5-乙炔基-2‘-脱氧尿苷)

所有产品仅用于科学研究,不得用于人体或动物实验。

目录号:HD00077

分子式:C11H12N2O5

分子量:252.22

纯度:≥95%

长期储存条件:Store in a tight container between 2-8℃, protect from light.

描述:Building blocks of nucleic acid

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5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation.

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参考文献

[1] Chenbo Zeng, et al. Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain Res. 2010 Mar 10;1319:21-32. 

[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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