Rezafungin is a novel echinocandin with exceptional stability and solubility and a uniquely long half-life allowing for front-loaded drug exposure with once-weekly dosing. Rezafungin has been shown comparable to other echinocandins, with activity against Candida spp. and Aspergillus spp. including subsets of echinocandin-resistant Candida auris and azole-resistant Aspergillus isolates. 

[1] Rezafungin: a novel antifungal for the treatment of invasive candidiasis.Future Microbiol. 2021 Jan;16(1):27-36. doi: 10.2217/fmb-2020-0217.