CAS 号: 41753-43-9 (中文同义词:人参皂苷 Rb1)
所有产品仅用于科学研究,不得用于人体或动物实验。
目录号:HD00193
分子式:C54H92O23
分子量:1109.29
纯度:≥95%
长期储存条件:Store in a tight container at -20℃.
描述:Main constituent of the root of Panax ginseng
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Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Also,it can inhibit IRAK-1 activation and phosphorylation of NF-κB p65.
[1] Joh EH, et al. Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation--the key step of inflammation. Biochem Pharmacol. 2011 Aug 1;82(3):278-86.
[2] Zhang J, et al. Ginsenosides Regulate PXR/NF-κB Signaling and Attenuate Dextran Sulfate Sodium-Induced Colitis. Drug Metab Dispos. 2015 Aug;43(8):1181-9.
[3] Jiang Y, et al. Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice. Oxid Med Cell Longev. 2015;2015:843721.
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