CAS 号： 1426953-21-0 （中文同义词：泰兰斯他汀 A）
所有产品仅用于科学研究，不得用于人体或动物实验。
目录号：HD00002
分子式：C28H41NO9
分子量：535.63
纯度：≥95%
长期储存条件：Store in a tight container at -20℃.
描述：DNA synthesis inhibitor
| 规格 | 价格 (EXW) | 是否有货 | 数量 | 加入购物车 |
|---|---|---|---|---|
| 10mg | ￥1500.00 | 有货 | - 1 + | |
| 25mg | ￥3300.00 | 有货 | - 1 + | |
| 50mg | ￥5200.00 | 有货 | - 1 + | |
| 100mg | ￥8400.00 | 有货 | - 1 + |
Thailanstatin A reveals low nanomolar to subnanomolar cytotoxicity against a variety of human cancer cell lines. The mechanism of action (MOA) of thailanstatin A is the inhibition of spliceosome assembly.
[1] Liu X, Biswas S, et al. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. J Nat Prod. 2013 Apr26;76(4):685-93.
[2] Puthenveetil S, Loganzo F, et al. Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) Payloads. Bioconjug Chem. 2016 Aug 17;27(8):1880-8.
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